The Role of Non-Coding RNAs in Myelodysplastic Neoplasms.
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ABSTRACT:
SUBMITTER: Georgoulis V
PROVIDER: S-EPMC10571949 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
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The Role of Non-Coding RNAs in Myelodysplastic Neoplasms.
Georgoulis Vasileios V Koumpis Epameinondas E Hatzimichael Eleftheria E
Cancers 20230930 19
Myelodysplastic syndromes or neoplasms (MDS) are a heterogeneous group of myeloid clonal disorders characterized by peripheral blood cytopenias, blood and marrow cell dysplasia, and increased risk of evolution to acute myeloid leukemia (AML). Non-coding RNAs, especially microRNAs and long non-coding RNAs, serve as regulators of normal and malignant hematopoiesis and have been implicated in carcinogenesis. This review presents a comprehensive summary of the biology and role of non-coding RNAs, in ...[more]
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