Mortality among people who inject drugs: a prospective cohort followed over three decades in Baltimore, MD, USA.

ABSTRACT:

Background and aims

During the past decades, people who inject drugs (PWID) have been impacted by the development of combination antiretroviral therapy (cART) to combat HIV/AIDS, the prescription opioid crisis and increased use of lethal synthetic opioids. We measured how these dynamics have impacted mortality among PWID in an urban US city.

Design

Prospective cohort study using data from the AIDS Linked to the Intravenous Experience (ALIVE).

Setting

Baltimore, MD, USA from 1988 to 2018.

Participants

A total of 5506 adult PWIDs (median age at baseline 37 years).

Measurements

Mortality was identified by linkage to National Death Index-Plus (NDI-Plus) and categorized into HIV/infectious disease (HIV/ID) deaths, overdose and violence-related (drug-related)

SUBMITTER: Sun J 

PROVIDER: S-EPMC10572098 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature