Thrombotic Alterations under Perinatal Hypoxic Conditions: HIF and Other Hypoxic Markers.

ABSTRACT: Hypoxia is considered to be a stressful physiological condition, which may occur during labor and the later stages of pregnancy as a result of, among other reasons, an aged placenta. Therefore, when gestation or labor is prolonged, low oxygen supply to the tissues may last for minutes, and newborns may present breathing problems and may require resuscitation maneuvers. As a result, poor oxygen supply to tissues and to circulating cells may last for longer periods of time, leading to life-threatening conditions. In contrast to the well-known platelet activation that occurs after reperfusion of the tissues due to an ischemia/reperfusion episode, platelet alterations in response to reduced oxygen exposition following labor have been less frequently investigated. Newborns overcome temporal hyp

SUBMITTER: Berna-Erro A 

PROVIDER: S-EPMC10572648 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature