Ontology highlight
ABSTRACT:
SUBMITTER: Samanic I
PROVIDER: S-EPMC10572715 | biostudies-literature | 2023 Sep
REPOSITORIES: biostudies-literature
Šamanić Ivica I Dadić Blanka B Sanader Maršić Željka Ž Dželalija Mia M Maravić Ana A Kalinić Hrvoje H Vrebalov Cindro Pavle P Šundov Željko Ž Tonkić Marija M Tonkić Ante A Vuković Jonatan J
International journal of molecular sciences 20230926 19
Point mutations in the <i>23S rRNA</i>, <i>gyrA</i>, and <i>gyrB</i> genes can confer resistance to clarithromycin (CAM) and levofloxacin (LVX) by altering target sites or protein structure, thereby reducing the efficacy of standard antibiotics in the treatment of <i>Helicobacter pylori</i> infections. Considering the confirmed primary CAM and LVX resistance in <i>H. pylori</i> infected patients from southern Croatia, we performed a molecular genetic analysis of three target genes (<i>23S rRNA</ ...[more]