Improved [¹⁸F]FDG PET/CT Diagnostic Accuracy for Infective Endocarditis Using Conventional Cardiac Gating or Combined Cardiac and Respiratory Motion Correction (CardioFreeze^TM).

ABSTRACT: Infective endocarditis (IE) is a serious and diagnostically challenging condition. [¹⁸F]FDG PET/CT is valuable for evaluating suspected IE, but it is susceptible to motion-related artefacts. This study investigated the potential benefits of cardiac motion correction for [¹⁸F]FDG PET/CT. In this prospective study, patients underwent [¹⁸F]FDG PET/CT for suspected IE, combined with a conventional cardiac gating sequence, a data-driven cardiac and respiratory gating sequence (CardioFreeze^TM), or both. Scans were performed in adherence to EANM guidelines and assessors were blinded to patients' clinical contexts. Final diagnosis of IE was established based on multidisciplinary consensus after a minimum of 4 months follow-up and surgical findings, whene

SUBMITTER: Ten Hove D 

PROVIDER: S-EPMC10572845 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature