Whey Protein Isolate/Calcium Silicate Hydrogels for Bone Tissue Engineering Applications-Preliminary In Vitro Evaluation.

ABSTRACT: Whey protein isolate (WPI) hydrogels are attractive biomaterials for application in bone repair and regeneration. However, their main limitation is low mechanical strength. Therefore, to improve these properties, the incorporation of ceramic phases into hydrogel matrices is currently being performed. In this study, novel whey protein isolate/calcium silicate (WPI/CaSiO₃) hydrogel biomaterials were prepared with varying concentrations of a ceramic phase (CaSiO₃). The aim of this study was to investigate the effect of the introduction of CaSiO₃ to a WPI hydrogel matrix on its physicochemical, mechanical, and biological properties. Our Fourier Transform Infrared Spectroscopy results showed that CaSiO₃ was successfully incorporated into the WPI hydro

SUBMITTER: Ivory-Cousins T 

PROVIDER: S-EPMC10573410 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature