Relationship between COMT Gene Polymorphism, Anxiety, and Pain Perception during Labour.

ABSTRACT:

Background

The COMT gene polymorphism is associated with neurological and psychiatric disorders and pain perception. The present study investigates the existence of anxiety and pain perception in relation to the COMT (catechol-O-methyltransferase) gene polymorphism in labouring women (during "natural" childbirth) with or without inhaled analgesia.

Methods

A total of 181 women who chose vaginal birth were enrolled in this study. To present the difference in pain perception, the parturients were divided into one group (n = 90) that chose labour analgesia with inhaled nitrous oxide (50% nitrous oxide and 50% oxygen) and one group (n = 91) without analgesia. The blood samples were taken during the pregnancy as a part of routine pregnancy controls in the hospital. T

SUBMITTER: Sanjug J 

PROVIDER: S-EPMC10573766 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature