The Triterpenoids from Munronia pinnata and Their Anti-Proliferative Effects.

ABSTRACT: Six new tirucallane-type triterpenoids, named munropenes A-F (1-6), were extracted from the whole plants of Munronia pinnata using a water extraction method. Their chemical structures were determined based on detailed spectroscopic data. The relative configurations of the acyclic structures at C-17 of munropenes A-F (1-6) were established using carbon-proton spin-coupling constants (^2,3J_C,H) and inter-proton spin-coupling constants (³J_H,H). Furthermore, the absolute configurations of munropenes A-F (1-6) were determined through high-performance liquid chromatography (HPLC), single-crystal X-ray diffraction, and electronic circular dichroism (ECD) analyses. The antiproliferative effect

SUBMITTER: Yang X 

PROVIDER: S-EPMC10574247 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature