Vitamin D and Child Neurodevelopment-A Post Hoc Analysis.

ABSTRACT:

Introduction

Vitamin D (VitD) has been shown to impact neurodevelopment. Studies have shown that higher 25-hydroxy-vitamin D (25(OH)D) concentrations (the indicator of vitD status) may be associated with better neurodevelopmental outcomes, although current data are conflicting. This study examined the relationship between total circulating 25(OH)D concentrations and neurodevelopmental outcomes in 3-5-year-old (3-5 yo) children.

Methods

In this study, pregnant women were randomized to receive 400 (standard dose), 2000, or 4000 IU vitD₃/day. Offspring then underwent the Brigance Screen at 3-5 yo. The 25(OH)D concentration was measured at birth and 3-5 yo. Relationships between Brigance scores and 25(OH)D and Brigance scores and vitamin D binding protein (VDBP) genot

SUBMITTER: Rodgers MD 

PROVIDER: S-EPMC10574578 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature