Ecological validity of cognitive fluctuations in dementia with Lewy bodies.

ABSTRACT:

Objectives

Cognitive fluctuations are a core clinical feature of dementia with Lewy bodies (DLB), but their contribution to the everyday functioning difficulties evident DLB are not well understood. The current study evaluated whether intraindividual variability across a battery of neurocognitive tests (intraindividual variability-dispersion) and daily cognitive fluctuations as measured by informant report are associated with worse daily functioning in DLB.

Methods

The study sample included 97 participants with consensus-defined DLB from the National Alzheimer's Coordinating Center (NACC). Intraindividual variability-dispersion was measured using the coefficient of variation, which divides the standard deviation of an individual's performance scores across 12 normed neurocog

SUBMITTER: Webber TA 

PROVIDER: S-EPMC10576013 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature