The value of arterial spin labelling (ASL) perfusion MRI in the assessment of post-treatment progression in adult glioma: A systematic review and meta-analysis.

ABSTRACT:

Background

The distinction between viable tumor and therapy-induced changes is crucial for the clinical management of patients with gliomas. This study aims to quantitatively assess the efficacy of arterial spin labeling (ASL) biomarkers, including relative cerebral blood flow (rCBF) and absolute cerebral blood flow (CBF), for the discrimination of progressive disease (PD) and treatment-related effects.

Methods

Eight articles were included in the synthesis after searching the literature systematically. Data have been extracted and a meta-analysis using the random-effect model was subsequently carried out. Diagnostic accuracy assessment was also performed.

Results

This study revealed that there is a significant difference in perfusion measurements between groups with P

SUBMITTER: Alsulami TA 

PROVIDER: S-EPMC10576519 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature