Exploring potential anti-inflammatory effects of medicinal cannabis.

ABSTRACT:

Purpose

Inflammation is thought to play a key role in malignant disease and may play a significant part in the expression of cancer-related symptoms. Cannabidiol (CBD) is a bioactive compound in cannabis and is reported to have significant anti-inflammatory properties.

Method

Serial C-reactive protein (CRP) levels were measured in all participants recruited to a randomised controlled trial of CBD versus placebo in patients with symptoms related to advanced cancer. A panel of inflammatory cytokines was measured over time in a subset of these patients.

Results

There was no difference between the two arms in the trajectory of CRP or cytokine levels from baseline to day 28.

Conclusion

We were unable to demonstrate an anti-inflammatory effect of CBD in cancer patien

SUBMITTER: Gurgenci T 

PROVIDER: S-EPMC10576726 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature