Idiopathic premature ventricular complexes treatment: Comparison of flecainide, propafenone, and sotalol.

ABSTRACT:

Background

Beta-blockers (BB) or dihydropyridine calcium channel blockers (CCBs) are still the first choices in the treatment of idiopathic premature ventricular complexes (PVCs), with low-modest efficacy. Antiarrhythmic drugs (AADs) of Ic class are moderate to highly efficient but the evidence on their benefits is still limited.

Aim

To compare effectiveness and safety of flecainide, propafenone, and sotalol in the treatment of symptomatic idiopathic PVCs.

Methods

Our single-center retrospective study analyzed 104 consecutive patients with 130 medication episodes of frequent idiopathic PVCs treated with AADs flecainide, propafenone (Ic class) or sotalol (III class). The primary outcome was complete/near complete reduction of PVCs after medication episode (PVCs burden

SUBMITTER: Kojic D 

PROVIDER: S-EPMC10577560 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature