Clinical characteristics of radiation-induced optic neuropathy: A single-center retrospective study.

ABSTRACT:

Purpose

To observe the clinical and imaging characteristics of radiation-induced optic neuropathy (RION).

Methods

We retrospectively reviewed the clinical data of 43 patients (69 eyes) who were diagnosed with RION at the Chinese PLA General Hospital from 2010 to 2021.

Results

The latency from radiotherapy to onset of visual loss ranged from 1 to 132 (36.33 ​± ​30.48) months. Optic disc pallor and optic disc edema were found in 27.0% (10/37) and 8.1% (3/37) of the eyes, respectively, within 2 months. After treatment, the best corrected visual acuity (BCVA) was restored in 24.6% (17/69) of the eyes and the final BCVA improved in 13.0% (9/69) of the eyes. An 82.5% (33/40) of the eyes with magnetic resonance imaging (MRI) showed enhancement of the affected optic nerve, mo

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10577828 | biostudies-literature | 2023 Aug-Sep

REPOSITORIES: biostudies-literature