Effects of empagliflozin on serum uric acid level of patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

ABSTRACT:

Background

Serum uric acid levels are higher in patients with type 2 diabetes and prediabetes compared to healthy individuals, and hyperuricemia causes a significant rate of complications and mortality through heart and kidney diseases. Accordingly, the present systematic review and meta-analysis aimed to investigate the effect of empagliflozin on serum uric acid levels.

Materials and methods

Electronic databases, including PubMed, Scopus, Web of Science, Cochrane, and Google Scholar, were used to search papers until May 22, 2023. Data analysis was conducted by STATA Version 14, and P-value < 0.05 were considered statistically significant.

Results

The results obtained from the combination of 12 studies with 7801 samples of diabetic patients indicated that in the empag

SUBMITTER: You Y 

PROVIDER: S-EPMC10577917 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature