Toxic metal mixtures in private well water and increased risk for preterm birth in North Carolina.

ABSTRACT:

Background

Prenatal exposure to metals in private well water may increase the risk of preterm birth (PTB) (delivery < 37 weeks' gestation). In this study, we estimated associations between arsenic, manganese, lead, cadmium, chromium, copper, and zinc concentrations in private well water and PTB incidence in North Carolina (NC).

Methods

Birth certificates from 2003-2015 (n = 1,329,071) were obtained and pregnancies were assigned exposure using the mean concentration and the percentage of tests above the maximum contaminant level (MCL) for the census tract of each individuals' residence at the time of delivery using the NCWELL database (117,960 well water tests from 1998-2019). We evaluated associations between single metals and PTB using adjusted logistic regression models. M

SUBMITTER: Eaves LA 

PROVIDER: S-EPMC10577978 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature