May Bradykinesia Features Aid in Distinguishing Parkinson's Disease, Essential Tremor, And Healthy Elderly Individuals?

ABSTRACT:

Background

Bradykinesia is the hallmark feature of Parkinson's disease (PD); however, it can manifest in other conditions, including essential tremor (ET), and in healthy elderly individuals.

Objective

Here we assessed whether bradykinesia features aid in distinguishing PD, ET, and healthy elderly individuals.

Methods

We conducted simultaneous video and kinematic recordings of finger tapping in 44 PD patients, 69 ET patients, and 77 healthy elderly individuals. Videos were evaluated blindly by expert neurologists. Kinematic recordings were blindly analyzed. We calculated the inter-raters agreement and compared data among groups. Density plots assessed the overlapping in the distribution of kinematic data. Regression analyses and receiver operating characteristic curve

SUBMITTER: Paparella G 

PROVIDER: S-EPMC10578222 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature