Motor Memory Consolidation Deficits in Parkinson's Disease: A Systematic Review with Meta-Analysis.

ABSTRACT:

Background

The ability to encode and consolidate motor memories is essential for persons with Parkinson's disease (PD), who usually experience a progressive loss of motor function. Deficits in memory encoding, usually expressed as poorer rates of skill improvement during motor practice, have been reported in these patients. Whether motor memory consolidation (i.e., motor skill retention) is also impaired is unknown.

Objective

To determine whether motor memory consolidation is impaired in PD compared to neurologically intact individuals.

Methods

We conducted a pre-registered systematic review (PROSPERO: CRD42020222433) following PRISMA guidelines that included 46 studies.

Results

Meta-analyses revealed that persons with PD have deficits in retaining motor skills

SUBMITTER: Cristini J 

PROVIDER: S-EPMC10578244 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature