Age Related Burden of Swallowing in Adult Patients Affected by Duchenne Muscular Dystrophy.

ABSTRACT:

Background

In Duchenne muscular dystrophy (DMD), dysphagia is a common but often overlooked symptom, which may affect quality of life (QoL). Its possible causes are progressive deterioration of muscle groups involved in swallowing function (oropharyngeal, inspiratory muscles) or impairment of autonomic function.

Objectives

In adult patients with DMD, we aimed to identify predictors of swallowing-related QoL and to compare swallowing-related QoL at different ages.

Methods

Forty-eight patients aged 30.0±6.6 years were enrolled. Questionnaires were administered: the Swallowing Quality of Life questionnaire (SWAL-QOL) for swallowing-related QoL assessment, and the Compass 31 for autonomic symptoms assessment. The Brooke Upper Extremity Scale was used for upper limbs muscu

SUBMITTER: Crescimanno G 

PROVIDER: S-EPMC10578249 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature