Lower Oxygen Tension and Intracranial Hemorrhage in Veno-venous Extracorporeal Membrane Oxygenation.

ABSTRACT:

Introduction and methods

We examined the relationship between 24-h pre- and post-cannulation arterial oxygen tension (PaO₂) and arterial carbon dioxide tension (PaCO₂) and subsequent acute brain injury (ABI) in patients receiving veno-venous extracorporeal membrane oxygenation (VV-ECMO) with granular arterial blood gas (ABG) data and institutional standardized neuromonitoring.

Results

Eighty-nine patients underwent VV-ECMO (median age = 50, 63% male). Twenty (22%) patients experienced ABI; intracranial hemorrhage (ICH) was the most common diagnosis (n = 14, 16%). Lower post-cannulation PaO₂ levels were significantly associated with ICH (66 vs. 81 mmHg, p = 0.007) and a post-cannulation PaO₂ level < 70 mmHg was more frequent in thes

SUBMITTER: Akbar AF 

PROVIDER: S-EPMC10578342 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature