Clinical scales in autoimmune encephalitis-A retrospective monocentric cohort study.

ABSTRACT:

Objective

Assessing severity of antibody-mediated encephalitis (AE) or paraneoplastic encephalitis (PE) requires valid and reliable scores to guide treatment decisions and predict outcome both in clinical routine and studies. We aimed to validate the prognostic value of the clinical assessment scale in autoimmune encephalitis (CASE) and the anti-NMDAR-encephalitis one-year functional status (NEOS) score in patients suffering from AE and PE in a large monocentric cohort.

Methods

We retrospectively applied the CASE and NEOS score to patients with definite AE and PE treated at a tertiary hospital. Correlations were established between the CASE and NEOS score and the modified Rankin scale (mRs). Multivariable analyses were calculated to identify predictors of outcome.

Results

SUBMITTER: Macher S 

PROVIDER: S-EPMC10578879 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature