Cognitive determinants of decisional capacity in neurodegenerative disorders.

ABSTRACT:

Objective

Cognitive contributions to decisional capacity are complex and not well understood. Capacity to consent for research has been linked to executive function, but executive function assessment tools are imperfect. In this study, we examine the relationship between decisional capacity and a newly developed executive function composite score and determine whether cognitive performance can predict impaired decisional capacity.

Methods

This is a cross sectional study of participants at the National Institutes of Health with frontotemporal dementia-amyotrophic lateral sclerosis spectrum disorders enrolled between 2017 and 2022. A structured interview tool was used to ascertain research decisional capacity. Study participant Uniform Data Set (v3.0) executive function (UDS3-

SUBMITTER: Portley M 

PROVIDER: S-EPMC10578892 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature