Dataset Information

Cross-sectional analysis of racial differences in hydration and neighborhood deprivation in young adults.

ABSTRACT:

Background

Inadequate hydration is associated with cardiovascular and kidney disease morbidity and all-cause mortality. Compared with White individuals, Black individuals exhibit a higher prevalence of inadequate hydration, which may contribute to racial health disparities. However, the underlying reasons for these differences in hydration remain unclear.

Objective

This cross-sectional study aimed to investigate whether neighborhood deprivation contributes to racial differences in hydration status.

Methods

We assessed 24 Black and 30 White college students, measuring 24-hour urine osmolality, urine flow rate, urine specific gravity, and plasma copeptin concentration. Participants recorded their food and fluid intake for 3 d to assess total water intake from food and beverages. Neighborhood socioeconomic deprivation was measured using a tract-level Area Deprivation Index.

Results

Black participants exhibited higher urine osmolality (640 [314] compared with 440 [283] mOsm/kg H₂O, respectively, P = 0.006) and lower urine flow rate (1.06 [0.65] compared with 1.71 [0.89] ml/min, respectively, P = 0.009) compared with White participants, indicating greater hypohydration among Black participants. Black participants reported lower total water intake from food and beverages than White participants (2.3 ± 0.7 compared with 3.5 ± 1.1 L/day, respectively, P < 0.01). Black participants exhibited higher copeptin than White participants (6.3 [3.1] compared with 4.5 [2.3] pmol/L, P = 0.046), and urine osmolality mediated 67% of the difference (P = 0.027). Black participants reported greater cumulative exposure to neighborhood deprivation during childhood (ages 0-18 y). Furthermore, neighborhood deprivation during childhood was associated with urine specific gravity (P = 0.031) and total water intake from food and beverages (P = 0.042) but did not mediate the racial differences in these measures.

Conclusion

Our data suggest that compared with White young adults, Black young adults are hypohydrated and exhibit higher plasma copeptin concentration, and that greater neighborhood deprivation is associated with chronic underhydration irrespective of race. This trial was registered at clinicaltrials.gov as NCT04576338.

SUBMITTER: Robinson AT

PROVIDER: S-EPMC10579046 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature

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Publications

Cross-sectional analysis of racial differences in hydration and neighborhood deprivation in young adults.

Robinson Austin T AT Linder Braxton A BA Barnett Alex M AM Jeong Soolim S Sanchez Sofia O SO Nichols Olivia I OI McIntosh Mason C MC Hutchison Zach J ZJ Tharpe McKenna A MA Watso Joseph C JC Gutiérrez Orlando M OM Fuller-Rowell Thomas E TE

The American journal of clinical nutrition 20230822 4

<h4>Background</h4>Inadequate hydration is associated with cardiovascular and kidney disease morbidity and all-cause mortality. Compared with White individuals, Black individuals exhibit a higher prevalence of inadequate hydration, which may contribute to racial health disparities. However, the underlying reasons for these differences in hydration remain unclear.<h4>Objective</h4>This cross-sectional study aimed to investigate whether neighborhood deprivation contributes to racial differences in ...[more]

PMID: 37619651

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Dataset Information

Cross-sectional analysis of racial differences in hydration and neighborhood deprivation in young adults.

Background

Objective

Methods

Results

Conclusion

Publications

Cross-sectional analysis of racial differences in hydration and neighborhood deprivation in young adults.

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