Effectiveness of COVID-19 vaccination against COVID-19 specific and all-cause mortality in older Australians: a population based study.

ABSTRACT:

Background

Few studies have examined effectiveness of COVID-19 vaccines against COVID-19 and all-cause mortality across different pandemic periods in 2022.

Methods

We used linked whole-of-population data from the 2021 Australian Census, Australian Immunisation Register, death registrations and other national datasets including migration data. Among 3.8 million adults aged 65+ years and >170,000 aged care residents, we used survival analysis to estimate vaccine effectiveness (VE) against COVID-19 specific mortality and all-cause mortality, by vaccine dose and time since receipt, adjusted for age, sex and other factors. We also estimated absolute COVID-19 mortality rates.

Findings

From January-May 2022 (Omicron BA.1/2), 3250 COVID-19 deaths occurred; from June-November

SUBMITTER: Liu B 

PROVIDER: S-EPMC10579525 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature