Amino acid profiles, disease activity, and protein intake in adult patients with Crohn's disease.

ABSTRACT:

Introduction

Crohn's disease (CD) is an immune-mediated inflammatory disorder of the gastrointestinal tract with a relapsing-remitting course. Amino acids (AAs) may play critical roles in the intestinal manifestations of disease, due to their involvement in many metabolic and immune functions. The present study aimed to explore serum AA concentrations in adult patients with CD, looking into their variations due to disease activity, surgery and protein content of diet. Eventually, the link between AAs and inflammatory markers was also assessed.

Methods

Consecutive adult patients aged 18-65 years with diagnosis of CD were recruited. All participants underwent anthropometry and were instructed to fill in a 3-day food record to assess protein intake. Disease activity was clinica

SUBMITTER: Cioffi I 

PROVIDER: S-EPMC10579601 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature