Use of clinical phenotypes to characterize emergency department patients administered intravenous opioids for acute pain.

ABSTRACT:

Objective

Individual experience with opioids is highly variable. Some patients with acute pain do not experience pain relief with opioids, and many report no euphoria or dysphoric reactions. In this study, we describe the clinical phenotypes of patients who receive intravenous opioids.

Methods

This was an emergency department-based study in which we enrolled patients who received an intravenous opioid. We collected 0 to 10 pain scores prior to opioid administration and 15 minutes after. We also used 0 to 10 instruments to determine how high and how much euphoria the patient felt after receipt of the opioid. Using a cutoff point of ≥50% improvement in pain and the median score on the high and euphoria scales, we assigned each participant to one of the following clinical pheno

SUBMITTER: Caplan M 

PROVIDER: S-EPMC10579725 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature