Manual annotation of Drosophila genes: a Genomics Education Partnership protocol.

ABSTRACT: Annotating the genomes of multiple species allows us to analyze the evolution of their genes. While many eukaryotic genome assemblies already include computational gene predictions, these predictions can benefit from review and refinement through manual gene annotation. The Genomics Education Partnership (GEP; https://thegep.org/) developed a structural annotation protocol for protein-coding genes that enables undergraduate student and faculty researchers to create high-quality gene annotations that can be utilized in subsequent scientific investigations. For example, this protocol has been utilized by the GEP faculty to engage undergraduate students in the comparative annotation of genes involved in the insulin signaling pathway in 27 Drosophila species, using D. melanogaster

SUBMITTER: Rele CP 

PROVIDER: S-EPMC10579860 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature