Effectiveness of Monovalent mRNA Vaccines Against Omicron XBB Infection in Singaporean Children Younger Than 5 Years.

ABSTRACT:

Importance

Literature on vaccine effectiveness of SARS-CoV-2 messenger RNA (mRNA) vaccines for children younger than 5 years is limited.

Objective

To report the effectiveness of monovalent mRNA vaccines against SARS-CoV-2 infection among Singaporean children aged 1 through 4 years during a COVID-19 pandemic wave of the Omicron XBB variant.

Design, setting, and participants

This was a population-based cohort study, conducted over a 6-month study period from October 1, 2022, through March 31, 2023, after the implementation of community vaccination among all Singaporean children aged 1 through 4 years. The study period was dominated by the Omicron XBB subvariant.

Exposure

Receipt of SARS-CoV-2 mRNA vaccines.

Main outcome measure

Vaccine effectiveness agains

SUBMITTER: Wee LE 

PROVIDER: S-EPMC10580153 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature