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Seroprotection against tetanus in southern Vietnam.


ABSTRACT:

Background

Ongoing tetanus cases and sporadic outbreaks of vaccine-preventable diseases associated with routine vaccination programmes remain problems in many low and middle-income countries, including Vietnam. With no human-to-human transmission or natural immunity, tetanus antibody levels indicate both individual risk of tetanus and gaps in vaccination programmes.

Methods

To investigate gaps in immunity to tetanus in Vietnam, a country with a historically high level of tetanus vaccination coverage, tetanus antibodies were measure by ELISA from samples selected from a long-term serum bank, established for the purposes of general-population seroepidemiological investigations in southern Vietnam. Samples were selected from 10 provinces, focussing on age-groups targeted by nat

SUBMITTER: Thwaites CL 

PROVIDER: S-EPMC10580288 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature