The associations of markers of endothelial dysfunction with hip fracture risk.

ABSTRACT: Endothelial dysfunction underlies the development of atherosclerotic vascular disease, which in turn is associated with osteoporotic fractures. Here, we examined the association of two markers of endothelial dysfunction with incident hip fracture risk in older adults but found no statistically significant associations between them.

Purpose/introduction

Endothelial dysfunction underlies the development of atherosclerotic vascular disease. Vascular disease, in turn, is associated with the risk of osteoporotic fractures, such as hip fractures. Here, we examine whether two measures of endothelial dysfunction are related to hip fracture risk.

Methods

Participants for this study were 2792 individuals (mean age 78.6 years) who had flow-mediated dilation (FMD) measured after ischemia

SUBMITTER: Barzilay JI 

PROVIDER: S-EPMC10580991 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature