Fungal co-expression network analyses identify pathogen gene modules associated with host insect invasion.

ABSTRACT: The broad host range fungal insect pathogen, Beauveria bassiana, has been commercialized as an alternative to chemical insecticides for pest control worldwide. B. bassiana represents a unique model system with which to examine host-pathogen interactions, and a wide range of genes and processes have been studied. However, significant aspects of virulence, particularly on the genomic scale, remain poorly studied. Here, we have combined available transcriptomes with three newly generated data sets for a combined total analysis of 76 deep-sequenced samples covering growth, development, stress responses, and infection during the life cycle of B. bassiana. Co-expression network analyses resulted in the identification of gene modules enriched during two critical stages of the

SUBMITTER: Huang S 

PROVIDER: S-EPMC10581046 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature