Efficient screening of adsorbed receptors for Salmonella phage LP31 and identification of receptor-binding protein.

ABSTRACT: The adsorption process is the first step in the lifecycle of phages and plays a decisive role in the entire infection process. Identifying the adsorption mechanism of phages not only makes phage therapy more precise and efficient but also enables the exploration of other potential applications and modifications of phages. Phage LP31 can lyse multiple Salmonella serotypes, efficiently clearing biofilms formed by Salmonella enterica serovar Enteritidis (S. Enteritidis) and significantly reducing the concentration of S. Enteritidis in chicken feces. Therefore, LP31 has great potential for many practical applications. In this study, we established an efficient screening method for phage infection-related genes and identified a total of 10 genes related to the adsorp

SUBMITTER: Ge H 

PROVIDER: S-EPMC10581130 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature