Does Long-Term Shift Work Increase the Risk of Dementia? A Systematic Review and Meta-Analysis.

ABSTRACT: Background: Shift work is associated with impaired sleep quality and disrupted circadian rhythms, but the way in which it increases the risk of dementia remains controversial. We conducted a systematic review and meta-analysis to assess the integrated risk of dementia with shift work. Methods: Searching in PubMed, Cochrane Library, and the Web of Science databases, the relative risks of dementia with shift work were extracted from 12 included studies with 3975 dementia cases from 84 492 participants. The subgroup analysis was stratified by age, gender, sample size, dementia cases, shift schedule, occupation, and follow-up time. Heterogeneity analysis and publication bias analysis were conducted for quality control. Results: The pooled risk ratios (RRs) of dementia with

SUBMITTER: Hai Y 

PROVIDER: S-EPMC10581141 | biostudies-literature | 2022 Jan-Dec

REPOSITORIES: biostudies-literature