Co-integrate Col3m bla _NDM-1-harboring plasmids in clinical Providencia rettgeri isolates from Argentina.

ABSTRACT: The first cases of bla _NDM in Argentina were detected in three Providencia rettgeri (Pre) recovered from two hospitals in Buenos Aires city in 2013. The isolates were genetically related, but the plasmid profile was different. Here, we characterized the bla _NDM-1-harboring plasmids of the first three cases detected in Argentina. Hybrid assembly obtained from short- and long-read sequencing rendered bla _NDM-1 in Col3M plasmids of ca. 320 kb (p15268A_320) in isolate PreM15268, 210 kb (p15758B_210) in PreM15758, and 225 kb (p15973A_225) in PreM15973. In addition, PreM15758 harbored a 98-kb circular plasmid (p15758C_98) flanked by a putative recombination site (hin-TnAs2), with 100% nucleotide ID and coverage wit

SUBMITTER: De Belder D 

PROVIDER: S-EPMC10581215 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature