Decompensated metabolic acidosis in the emergency department: Epidemiology, sodium bicarbonate therapy, and clinical outcomes.

ABSTRACT:

Objective

This article aims to describe the epidemiology of decompensated metabolic acidosis, the characteristics of sodium bicarbonate (SB) administration and outcomes in emergency department (ED) patients.

Design

This is a retrospective cohort study.

Setting

ED of a tertiary referral hospital in Melbourne, Australia.

Participants

Adult patients presenting to the ED between 1 July 2011 and 20 September 2020 with decompensated metabolic acidosis diagnosed on arterial blood gas (ABG).

Main outcome measures

We compared characteristics between those treated with or without SB. We studied SB administration characteristics, change in laboratory variables, factors associated with use and dose, and clinical outcomes.

Results

Among 753,613 ED patients, 31

SUBMITTER: Guy C 

PROVIDER: S-EPMC10581257 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature