Genetic testing practices among specialist physicians who treat prostate cancer A Canadian, cross-sectional survey.

ABSTRACT:

Introduction

In patients with prostate cancer (PCa), the identification of an alteration in genes associated with homologous recombination repair (HRR) has implications for prognostication, optimization of therapy, and familial risk mitigation. The aim of this study was to assess the genomic testing landscape of PCa in Canada and to recommend an approach to offering germline and tumor testing for HRR-associated genes.

Methods

The Canadian Genitourinary Research Consortium (GURC) administered a cross-sectional survey to a largely academic, multidisciplinary group of investigators across 22 GURC sites between January and June 2022.

Results

Thirty-eight investigators from all 22 sites responded to the survey. Germline genetic testing was initiated by 34%, while 45% requi

SUBMITTER: Yip SM 

PROVIDER: S-EPMC10581730 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature