Poly(ethylene imine)-chitosan carbon dots: study of its physical-chemical properties and biological in vitro performance.

ABSTRACT: Carbon dots (CDs) have been quickly extended for nanomedicine uses because of their multiple applications, such as bioimaging, sensors, and drug delivery. However, the interest in increasing their photoluminescence properties is not always accompanied by cytocompatibility. Thus, a knowledge gap exists regarding their interactions with biological systems linked to the selected formulations and synthesis methods. In this work, we have developed carbon dots (CDs) based on poly (ethylene imine) (PEI) and chitosan (CS) by using microwave irradiation, hydrothermal synthesis, and a combination of both, and further characterized them by physicochemical and biological means. Our results indicate that synthesized CDs have sizes between 1 and 5 nm, a high presence of amine groups on the surface, and

SUBMITTER: Santos N 

PROVIDER: S-EPMC10581970 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature