Application of single wrist-wearable accelerometry for objective motor diary assessment in fluctuating Parkinson's disease.

ABSTRACT: Advanced Parkinson's disease (PD) is characterized by motor fluctuations including unpredictable oscillations remarkably impairing quality of life. Effective management and development of novel therapies for these response fluctuations largely depend on clinical rating instruments such as the widely-used PD home diary, which are associated with biases and errors. Recent advancements in digital health technologies provide user-friendly wearables that can be tailored for continuous monitoring of motor fluctuations. Their criterion validity under real-world conditions using clinical examination as the gold standard remains to be determined. We prospectively examined this validity of a wearable accelerometer-based digital Parkinson's Motor Diary (adPMD) using the Parkinson's Kinetigraph (PKG

SUBMITTER: Lohle M 

PROVIDER: S-EPMC10582031 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature