Identification of key biomarkers and associated pathways of pancreatic cancer using integrated transcriptomic and gene network analysis.

ABSTRACT: Pancreatic cancer shows malignancy around the world standing in 4th position for causing death globally. This cancer is majorly divided into exocrine and neuroendocrine where exocrine pancreatic ductal adenocarcinoma is observed to be nearly 85% of cases. The lack of diagnosis of pancreatic cancer is considered to be one of the major drawbacks to the prognosis and treatment of pancreatic cancer patients. The survival rate after diagnosis is very low, due to the higher incidence of drug resistance to cancer which leads to an increase in the mortality rate. The transcriptome analysis for pancreatic cancer involves dataset collection from the ENA database, incorporating them into quality control analysis to the quantification process to get the summarized read counts present in collected samp

SUBMITTER: Rambabu M 

PROVIDER: S-EPMC10582056 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature