A Competitive High-Throughput Screening Platform for Designing Polylactic Acid-Specific Binding Peptides.

ABSTRACT: Among biobased polymers, polylactic acid (PLA) is recognized as one of the most promising bioplastics to replace petrochemical-based polymers. PLA is typically blended with other polymers such as polypropylene (PP) for improved melt processability, thermal stability, and stiffness. A technical challenge in recycling of PLA/PP blends is the sorting/separation of PLA from PP. Material binding peptides (MBPs) can bind to various materials. Engineered MBPs that can bind in a material-specific manner have a high potential for material-specific detection or enhanced degradation of PLA in mixed PLA/PP plastics. To obtain a material-specific MBP for PLA binding (termed PLA^bodies ), protein engineering of MBP Cg-Def for improved PLA binding specificity is reported in this work. In detail

SUBMITTER: Lu Y 

PROVIDER: S-EPMC10582454 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature