COVID-19 vaccination for children with pulmonary hypertension: efficacy, safety and reasons for opting against vaccination.

ABSTRACT:

Objective

To determine the reasons why pulmonary hypertension (PH) children refused vaccination against COVID-19, evaluate the safety and efficacy of COVID-19 vaccine in PH children.

Study design

This retrospective cohort study included congenital heart disease-associated pulmonary arterial hypertension (CHD-PAH) and bronchopulmonary dysplasia associated PH (BPD-PH) children who were divided into vaccinated group and non-vaccinated group. Univariate logistic regression analysis and multivariate logistic regression analysis were conducted to explore the reasons why PH children refused COVID-19 vaccine. Then, the prevalence, the number of symptoms, and the severity of COVID-19 disease were compared between the vaccinated and unvaccinated groups.

Result

We included 73 ch

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC10582704 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature