Adult Attention-Deficit/Hyperactivity Disorder and the Risk of Dementia.

ABSTRACT:

Importance

Evidence that adult attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk of dementia is scarce and inconsistent, and potential sources of bias are untested.

Objective

To examine the association between adult ADHD and the risk of dementia.

Design, setting, and participants

This prospective national cohort study consisted of 109 218 members of a nonprofit Israeli health maintenance organization born between 1933 and 1952 who entered the cohort on January 1, 2003, without an ADHD or dementia diagnosis and were followed up to February 28, 2020. Participants were aged 51 to 70 years in 2003. Statistical analysis was conducted from December 2022 to August 2023.

Exposure

Adult ADHD was a time-varying covariate, classified as

SUBMITTER: Levine SZ 

PROVIDER: S-EPMC10582792 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature