Predictors and prognosis of population-based subjective cognitive decline: longitudinal evidence from the Caerphilly Prospective Study (CaPS).

ABSTRACT:

Objectives

To understand associations between the subjective experience of cognitive decline and objective cognition. This subjective experience is often conceptualised as an early step towards neurodegeneration, but this has not been scrutinised at the population level. An alternative explanation is poor meta-cognition, the extreme of which is seen in functional cognitive disorder (FCD).

Design

Prospective cohort (Caerphilly Prospective Study).

Setting

Population-based, South Wales, UK.

Participants

This men-only study began in 1979; 1225 men participated at an average age of 73 in 2002-2004, including assessments of simple subjective cognitive decline (sSCD, defined as a subjective report of worsening memory or concentration). Dementia outcomes were followed

SUBMITTER: Ball HA 

PROVIDER: S-EPMC10582873 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature