Breast feeding in infants diagnosed with phenylketonuria (PKU): a scoping review.

ABSTRACT:

Background

Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, breast feeding is the optimal nutrition for an infant and continuing breast feeding for infants with PKU is recommended by European guidelines. However, human breast milk contains Phe in varying quantities, and therefore, the effects breast feeding might have on infants with PKU needs careful consideration.

Aim

To assess the effects of breast feeding (exclusive or partial) compared with low-Phe formula feeding in infants diagnosed with PKU, on blood Phe levels, growth and neurodevelopmental scores.

Methods

The Cochrane Inborn

SUBMITTER: Kalvala J 

PROVIDER: S-EPMC10582905 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature