Identification of CKS2 as a novel prognostic biomarker and potential therapeutic target for oral squamous cell carcinoma.

ABSTRACT:

Background

The cyclin-dependent kinase subunit 2 (CKS2) is recognized to have a substantial impact on the pathogenesis and advancement of several malignant neoplasms. Nevertheless, its biological function and prognostic significance in oral squamous cell carcinoma (OSCC) have yet to be thoroughly investigated. Our primary objective was to clarify the contribution of CKS2 in the progression and prognosis of OSCC.

Methods

We first conducted a thorough examination of online databases to investigate the expression of CKS2, and subsequently corroborated our discoveries by analyzing clinical specimens that we collected. According to the clinicopathological data, we then explored the prognostic significance of CKS2. Furthermore, we predicted the role of

SUBMITTER: Qiu D 

PROVIDER: S-EPMC10583009 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature