Receiver operating characteristic (ROC) to determine cut-off points of clinical and biomolecular markers to discriminate mortality in severe COVID-19 living at high altitude.

ABSTRACT:

Background

In 2020, Ecuador had one of the highest death rates because of COVID-19. The role of clinical and biomolecular markers in COVID disease prognosis, is still not well supported by available data. In order for these markers to have practical application in clinical decision-making regarding patient treatment and prognosis, it is necessary to know an optimal cut-off point, taking into consideration ethnic differences and geographic conditions.

Aim

To determine the value of clinical and biomolecular markers, to predict mortality of patients with severe COVID-19 living at high altitude.

Methods

In this study, receiver operating characteristic (ROC) curves, area under the curve (AUC) of ROC, sensitivity, specificity and likelihood ratios were calculated to determi

SUBMITTER: Velez-Paez JL 

PROVIDER: S-EPMC10583315 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature