Elucidating regulatory processes of intense physical activity by multi-omics analysis.

ABSTRACT:

Background

Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations, such as firefighting, law enforcement, military, and sports. A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work environment.

Methods

To study regulatory processes in intense physical activity simulating real-life conditions, we performed a multi-omics analysis of three biofluids (blood plasma, urine, and saliva) collected from 11 wildland firefighters before and after a 45 min, intense exercise regimen. Omics profiles post- versus pre-exercise were compared by Student's t-test followed by pathway analysis and comparison between the

SUBMITTER: Nakayasu ES 

PROVIDER: S-EPMC10583322 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature