Effect of immunology biomarkers associated with hip fracture and fracture risk in older adults.

ABSTRACT: Osteoporosis is a skeletal disease that can increase the risk of fractures, leading to adverse health and socioeconomic consequences. However, current clinical methods have limitations in accurately estimating fracture risk, particularly in older adults. Thus, new technologies are necessary to improve the accuracy of fracture risk estimation. In this observational study, we aimed to explore the association between serum cytokines and hip fracture status in older adults, and their associations with fracture risk using the FRAX reference tool. We investigated the use of a proximity extension assay (PEA) with Olink. We compared the characteristics of the population, functional status and detailed body composition (determined using densitometry) between groups. We enrolled 40 participants, inc

SUBMITTER: Cedeno-Veloz BA 

PROVIDER: S-EPMC10583364 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature