Connective tissue nevus misdiagnosed as juvenile localized scleroderma.

ABSTRACT:

Background

Connective tissue nevi (CTN) are congenital hamartomas caused by excessive proliferation of dermis components. In children, CTN can mimic juvenile localized scleroderma (JLS), an immune mediated skin disorder that requires aggressive immunosuppression.

Objectives

Aim of our study was to describe a series of pediatric patients with CTN misdiagnosed as JLS and the discerning characteristics between the two conditions.

Methods

Retrospective analysis of children referred to our Center during the last two decades for JLS who received a final diagnosis of CTN. Clinical, laboratory, histopathological and instrumental data (MRI and thermography) were collected and compared with those with JLS.

Results

Seventeen patients with mean age at onset 4.6 years enter

SUBMITTER: Tirelli F 

PROVIDER: S-EPMC10583392 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature