In-depth magnetometry and EPR analysis of the spin structure of human-liver ferritin: from DC to 9 GHz.

ABSTRACT: Ferritin, the major iron storage protein in organisms, stores iron in the form of iron oxyhydroxide most likely involving phosphorous as a constituent, the mineral form of which is not well understood. Therefore, the question of how the ca. 2000 iron atoms in the ferritin core are magnetically coupled is still largely open. The ferritin core, with a diameter of 5-8 nm, is encapsulated in a protein shell that also catalyzes the uptake of iron and protects the core from outside interactions. Neurodegenerative disease is associated with iron imbalance, generating specific interest in the magnetic properties of ferritin. Here we present 9 GHz continuous wave EPR and a comprehensive set of magnetometry techniques including isothermal remanent magnetization (IRM) and AC susceptibility to

SUBMITTER: Bossoni L 

PROVIDER: S-EPMC10583656 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature